Intracranial hemorrhage
Conditions
Interventions
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 years old and more; 2. Acute stroke syndrome due to primary intracranial haemorrhage(ICH)confirmed by CT or MRI scan, and the volume of hematoma is between 30 and 50 ml in supratentorial haemorrhage or above 10 ml in cerebellar haemorrhage; 3. GCS > 5; 4. At least two systolic blood pressure(BP) measurements of =150 mmHg and = 220mmHg, record = 5min apart; 5. Meet the indication of surgery and receive the surgery; 6. Agree to participate in this clinic trail and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Known definite indication to BP lowering treatment (e.g. very high systolic BP>220mmHg; hypertensive encephalopathy; aortic dissection); known definite contraindication to BP lowering treatment (e.g. the high BP is caused by the increasing of the intracranial pressure which is called Cushing reaction; severe cerebral or carotid stenosis, severe renal failure); 2. The intracranial haemorrhage is caused by secondary factors (e.g. arteriovenous malformation; Moya Moya disease; Anticoagulants correlation haemorrhage; tumor stroke); 3. Known definite contraindication to operation; 4. History of ischemic stroke; 5. Known advanced dementia or disability before ICH happen; 6. Concomitant medical illness that would interfere with outcome assessments and follow-up(e.g. advanced cancer; severe cardiovascular disease).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| combined endpoin tof death and dependence; | — |
Secondary
| Measure | Time frame |
|---|---|
| Health related quality of life index;incidence of rebleeding;incidence of ischemic stroke; | — |
Countries
China
Contacts
Public ContactChao You
West China Hospital, Sichuan University
Outcome results
None listed