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The radiation toxicty of Non-squamous Cell Lung Cancer patients by irradiation combined with pemetrexed

The radiation toxicty of Non-squamous Cell Lung Cancer patients by irradiation combined with pemetrexed

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-13004184
Enrollment
Unknown
Registered
2013-01-13
Start date
2013-08-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lung cancer

Interventions

A:Pemetrexed/platinum
B:Docetaxel/Cisplatinl

Sponsors

GuiZhou Cancer Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1) histologically or cytology confirmed inoperable NSCLC; 2) Aged 18–70 years; 3) a Karnofsky Performance Status score =70%; 4) adequate bone marrow, liver and renal function; neutrophils = 1.5×10^9/L, platelets 80×10^9/L, hemoglobin =80g/L, AST and ALT =2× the upper limit of the institutional normal range, total bilirubin =1.25× the upper limit of the institutional normal range, and creatinine concentration =120 umol/L; 5) no contraindication for radiotherapy and chemotherapy; 6) patients were expected to receive thoracic radiotherapy at a dose of =40 Gy in 20 fractions.

Exclusion criteria

Exclusion criteria: 1) a history involving thoracic surgery, radiotherapy or chemotherapy; 2) pregnancy or lactation; 3) previous malignancy or other concomitant malignant disease.

Design outcomes

Primary

MeasureTime frame
overall survival (OS), progression-free survival (PFS), and tumor control;

Countries

China

Contacts

Public ContactSu Shengfa

Department of Thoracic Oncology, GuiZhou Cancer Hospital

sushengfa2005@163.com+86 13608550432

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 24, 2026