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Effect of Euthyrox intervention on In vitro fertilization outcomes among euthyroid women with TPOAb

Effect of Euthyrox Intervention on In Vitro Fertilization Outcomes among Euthyroid Women with TPOAb----a Randomized Open Labeled Trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-13004097
Enrollment
Unknown
Registered
2013-12-11
Start date
2012-06-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

autoimmune thyroiditis

Interventions

Intervention group:levothyroxine
Control:No treatment
levothyroxine for hypothyrodism case if anyone after trial (waiting list)

Sponsors

Endocrinological department, Peking University Third Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
23 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. To be aged from 23 to 40 year; 2. TPOAb positive; 3. Euthyroid function; 4. First or second IVF circle; 5. Fresh cycle.

Exclusion criteria

Exclusion criteria: 1. History of thyroid disease (hyper orhypo thyroid dysfunction, post radio-iodine therapy, or thyroid tumor); 2. Recurrent Miscarriage; 3. Premature ovary failure; 4. Other endocrinology glands disorder; 5. Liver dysfunction (ALT or AST >=3 times of the normal upper limit); 6. Renal failure: CCr >=130 umol/L; 7. Heart failure, Arrythmia, Myocardial infarctionangina pectoris; 8. Psychiatric disorder.

Design outcomes

Primary

MeasureTime frame
micarriage rate;—

Secondary

MeasureTime frame
Clinical pregnancy rate;Live Birth Rate;Preterm birth rate;—

Countries

China

Contacts

Public ContactHong Tianpei, Qiao Jie

Peking Univeristy, Third Hospital

TPHO66@bjmu.edu.cn+86 15611908212, 15611908108

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 25, 2026