atrial fibrillation
Conditions
Interventions
Probucol +metoprolol:Probucol +metoprolol
Sponsors
Second Hospital of Tianjin Medical University
Eligibility
Sex/Gender
All
Age
25 Years to 75 Years
Inclusion criteria
Inclusion criteria: a history of paroxysmal atrial fibrillation within preceding 6 months, which should be demonstrated on electrocardiograms (ECG) within 6 months before enrollment, according to the diagnosis standard of 2010 ESC atrial fibrillation prevention guide
Exclusion criteria
Exclusion criteria: (1) persistent AF with a duration >=1 week, and/or permanent AF; (2) serious left main coronary artery disease in coronary angiography; (3) heart failure (NYHA III or IV); (4) history of coronary artery bypass surgery or PCI; (5) history of acute or old myocardial infarction; (6) cardiomyopathy; (7) valvular heart disease; (8) contraindication of Probucol and/or metoprolol; (9) serious liver/renal dysfunction; (10) history of unstable angina pectoris; (11) stroke or transient ischemic attack (TIA) history within preceding three months; (12) must take anti-arrhythmic drugs (including Chinese medicine anti-arrhythmic drugs), except beta blockers; (13) patients have had Probucol and/or metoprolol but cant accept the washout period for 2 weeks; (14) a judgment by the attending physician that patient participation would be inappropriate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| atrial fibrillation recurrence; | — |
Contacts
Public ContactTong Liu
Second Hospital of Tianjin Medical University
Outcome results
None listed