The effect of lavage fluid suspension height on hemodynamics and respiratory mechanics during pulmonary alveolar proteinosis lavage

The effects of whole lung lavage on hemodynamics and respiratory mechanics

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-13004074

Enrollment

Unknown

Registered

2013-12-27

Start date

2014-01-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary alveolar proteinosis

Interventions

1:lavage fluid suspension height

2:Capacity control

Eligibility

Sex/Gender

Male

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: pulmonary alveolar proteinosis patients subjected to whole lung lavage

Exclusion criteria

Exclusion criteria: NA

Design outcomes

Primary

Measure	Time frame
Heart Rate;mean arterial pressure;central venous pressure;cardiac output index;cardiac stroke volume index;peripheral vascular resistance index;intrathoracic blood volume;extravascular lung water;stroke volume variation;Left ventricular contractility index (dPmax);Pulse oxygen saturation(SPO2);end expiratory carbon dioxide;tidal volume (VT);minute ventilation (VM);peak airway pressure (Peak);plateau airway pressure (Plat);body temperatur;	—

Measure

Time frame

Heart Rate;mean arterial pressure;central venous pressure;cardiac output index;cardiac stroke volume index;peripheral vascular resistance index;intrathoracic blood volume;extravascular lung water;stroke volume variation;Left ventricular contractility index (dPmax);Pulse oxygen saturation(SPO2);end expiratory carbon dioxide;tidal volume (VT);minute ventilation (VM);peak airway pressure (Peak);plateau airway pressure (Plat);body temperatur;

—

Secondary

Measure	Time frame
chest CT imaging change before and after lavage;blood gas analysis change before and after lavage;complications occurred during lavag;	—

Contacts

Public ContactLan Lan

The first Affiliated hospital of Guangzhou Medical University

vapour2046@126.com+86 13660756820

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026