Post Operative Illes
Conditions
Interventions
QWE:QQE
QWE:QQE placebo
Sponsors
Renmin Hospital of Beijing University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Open abdominal gastrointestinal surgery; (2) Surgery with general anesthesia, and intravenous analgesia after surgey; (3) Aged 18-75; (4) Volantarily to sign the informed consent file.
Exclusion criteria
Exclusion criteria: (1) Patients under rectal anastomosis or intestinal fistulation; (2) Patients with extensive malignant tumor abdominal cavity metastasis or adhesion; or acute intestinal obstruction; (3) Patients with acidosis/HONKC/severe dehydration/severe electrolyte disorder; (4) Patients complicated with severe cardiac-cerebral vascular disease or severe primary hematopoietic system disease; (5) Patients of Type 1 or 2 diabetic with fasting blood-glucose>8mmol/L; (6) Patients with ALT>1.5 times upper normal limit or Cr> upper normal limit; (7) BMI>30 or BMI2 drugs); (9) Pregnant or lactating women,or who has short term plan for pregnancy; (10) Patients participated in any clinical trials in the past 4 weeks. (11) Patients, decided by the investigator, not suitable for the trial, such as with excessively long operation time, severe complication, unstable respiration and circulation system 12 hours after surgery, ect.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to first passing flatus: time to first passing flatus after surgery;Time to first passage of stool: time to first passage of stool after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| The time to the first bowel sounds by doctor auscultation;Time to first tolerent of solid food;Theoretical discharge time; | — |
Countries
China
Contacts
Public ContactChen Xie
Beijing SNYK Pharmaceutical Ltd
Outcome results
None listed