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Effects and mechanisms of transcranial magnetic stimulation on motor disorder in children with cerebral palsy

Effects and mechanisms of transcranial magnetic stimulation on motor disorder in children with cerebral palsy

Status
Recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-13004033
Enrollment
Unknown
Registered
2013-12-16
Start date
2014-01-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cerebral palsy

Interventions

low-frequency rTMS:1Hz rTMS stimulation
high-frequency rTMS:5Hz rTMS stimulation
sham rTMS:sham rTMS stimulation

Sponsors

Guangzhou Women and Children's Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 18 Years

Inclusion criteria

Inclusion criteria: 1. diagnosis of hemiplegic cerebral palsy according to clinical criteria; 2. minimum age of 6 years old and maximum age of 18 years old; 3. a 20–80% difference between two hands; 4. children and parents informed consent to accept the test.

Exclusion criteria

Exclusion criteria: 1. any health problems that are not associated with cerebral palsy,and uncontrolled seizures; 2. contraindications of rTMS treatment,such as skull defects repaired with metallic materials,etc; 3. contractures that limit functional arm and hand use; 4. received botulinum toxin injection in the upper limb during the last 6 months or who wish to receive it within the period of study; 5. orthopedic surgery on their involved upper limb; 6. visual and balance problems that would prevent them from carrying out the intervention or assessment; 7. received other interventions that affect this study.

Design outcomes

Primary

MeasureTime frame
sEMG;fMRI;nine-peg hole test;ROM;

Countries

China

Contacts

Public ContactXu Kaishou

Guangzhou Women and Children's Medical Center

xksyi@126.com+86 13422250582

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026