The effects of remifentanil on MAC-BAR and catecholamine-BAR of inhaled anesthetics in patients undergoing laparoscopic surgery

The effects of different target-controlled concentrations of remifentanil on MAC-BAR and catecholamine-BAR of sevoflurane in gynecological patients undergoing laparoscopic surgery

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-13004005

Enrollment

Unknown

Registered

2013-12-18

Start date

2013-12-17

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with laparoscopic surgery

Interventions

isoflurane group:The plasma target concentration of remifentanil was 0, 1 and 2ng/ml in the three subgroups, respectively.

group of sevoflurane:The plasma target concentration of remifentanil was 0, 1 and 2 ng/ml in the three subgroups, respectively

Eligibility

Sex/Gender

Female

Age

20 Years to 50 Years

Inclusion criteria

Inclusion criteria: All gynecology patients were ASA physical status I or II, aged between 20 and 45 yrs old.

Exclusion criteria

Exclusion criteria: Exclusion criteria were history of cardiac, pulmonary, liver, brain or renal disease; drug or alcohol abuse; significant obesity (body mass index > 30 kg/m2); current use of any vasoactive medications; current use of any medications known to affect MAC or sympathetic responses; and contraindication for inhalational induction.

Design outcomes

Primary

Measure	Time frame
minimal alveolar concentration;catecholamin;	—

Countries

China

Contacts

Public ContactYang XiaoLin

yang_xl_yang@126.com+86 0817-2262434

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 18, 2026