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Basic and Applied Research on under-collected whole blood

Effect of leukodepletion by filtration/irradiation on the impact of erythrocytes of undercollected whole blood and underlying mechanisms

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-13003967
Enrollment
Unknown
Registered
2013-12-05
Start date
2014-03-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

under-collected whole blood

Interventions

UC-RBCs :transfusion of UC-RBCs
UC-RBCs with leukodepletion by filtration:transfusion of UC-RBCs with leukodepletion by filtration
UC-RBCs with leukodepletion by irradiation:transfusion of UC-RBCs with leukodepletion by irradiation
UC-RBCs with leukodepletion by filtration/irradiat:transfusion of UC-RBCs with leukodepletion by filtration/irradiation

Sponsors

Jiangsu Province Blood Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Written informed consent; 2. Aged between 18 and 65; 3. weight>/=50kg; 4. internal patients whose Hb value is below 70 g/L, suffere from one or more clinical symptoms such as pallor, giddiness, anhelation, or palpitation; 5. Patients who will undergo a preplanned surgerie, whose transfusion is considered necessary by surgery.

Exclusion criteria

Exclusion criteria: 1. active bleeding; 2. hemolytic disease,such as hereditary hemolytic anemia,red-cell fragement syndrome,drug induced immune hemolytic anemia, hypersplenism etc; 3. autoimmune diseases, such as systemic lupus erythemalosus,autoimmune hemolytic anemia, DIC, systemic vasculitis etc.; 4. serious systemic disease or complications; 5. The existence of the peripheral nervous system disorders or significant neurological disorders and a history of central nervous system disorders, sucn as patients with alcoholism, drug addiction or mental illness; 6. Pregnant or lactating woman, or child-bearing period woman.

Design outcomes

Primary

MeasureTime frame
blood routine examination;Transfusion adverse reaction;

Countries

China

Contacts

Public ContactWenbiao LIANG

Jiangsu Province Blood Center

thibaut@126.com+86 18913826070

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 5, 2026