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Clinical Study on Dose-effect Relationship of Maxing Ganshi Decoction on Treating Children with Bronchial pneumonia (Wind-heat Blocking the Lung)-4

Study on Dose-effect Relationship of Classical famous Prescription Based on Clinical Evaluation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-13003955
Enrollment
Unknown
Registered
2013-11-30
Start date
2013-12-15
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Children with Bronchial pneumonia(Wind-heat Blocking the Lung)

Interventions

Maxingganshi group:1.TCM decoction: MA HUANG 6g, XING REN 6g, SHENG SHI GAO 24g, GAN CAO 6g
2.Basic therapy
Placebo group:1. Placebo: Corn flour, Brown sugar, Sucrose Octaacetate
2. Basic therapy

Sponsors

First Teaching Hospital of Tianjin University of TCM
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 6 Years

Inclusion criteria

Inclusion criteria: 1. The disease has been diagnosed as pneumonia (wind-heat blocking the lung); 2. Pneumonia course is less than 48 hours; 3. The highest temperature is beyond 37.3 degree during 24 hours before the beginning of the trial; 4. Aged 3 to 6 years old; body weight >/=14kg; 5. WBC </=10*10^9/L, N<70%; 6. normal CRP; 7. Hospitalized patients; 8. Children's legal guardians have signed the ICF.

Exclusion criteria

Exclusion criteria: 1. the patient who has heart failure, respiratory failure, the toxic encephalopathy, exudative pleurisy and other complications; 2. The one who clearly merged with bacterial infection; 3. The one who has some serious primary diseases of heart, liver, kidney and hematopoietic system, the mentally illness. Such as: (1) arrhythmias with clinical significance; (2) ALT: more than double than the upper limit of normality; (3) Scr >150 umol/ L, UN>10mmol/L, and/or and proteinuria >+, or / and erythrocyte urine>+; 4. According to the investigator's judgment, the one who has the possibility in reducing enrollment; 5. Children who can't cooperate or are participating in clinical trials of other drugs; 6. Allergic constitution; 7. According to the doctor's judgment, it's likely to cause the loss to follow.

Design outcomes

Primary

MeasureTime frame
Efficacy of Disease;—

Secondary

MeasureTime frame
Efficacy of TCM syndrome;Efficacy of individual symptoms (fever, cough, sputum);Time for temperature completely clearance;—

Countries

China

Contacts

Public ContactRONG MA

First Teaching Hospital of Tianjin University of TCM,Pediatric Department

mr1974@163.com+86 022 27432012

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026