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A randomised prospective trial comparing Nissen fundoplication with Toupet fundoplication for gastro-oesophageal reflux disease

Comparative Appraisal between Laparoscopic Nissen and Toupet Fundoplication for Gastroesophageal Reflux Disease

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-13003945
Enrollment
Unknown
Registered
2013-12-02
Start date
2010-01-15
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastro-oesophageal reflux disease

Interventions

1:Laparoscopic Nissen fundoplication (LNF)
2:Laparoscopic Toupet fundoplication, LTF

Sponsors

Changzheng Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 82 Years

Inclusion criteria

Inclusion criteria: 1. adults older than 20 years; 2. typical gastro-oesophageal reflux symptoms such as heartburn, regurgitation, and acid reflux; 3. abnormally low LESP; and 4. acid reflux documented with 24-h oesophageal pH monitoring.

Exclusion criteria

Exclusion criteria: 1. abnormal gastrointestinal peristalsis with refractory gas bloating or constipation; 2. normal LESP; 3. negative acid reflux testing by pH monitoring; or 4. refusal to undergo long-term follow up or to sign informed consent.

Design outcomes

Primary

MeasureTime frame
incidence of dysphagia;recurrence of reflux;degree of satisfaction;Quality of life;lower oesophageal sphincter pressure;—

Countries

China

Contacts

Public ContactChengxiang Shan

Changzheng Hospital

chengxiangshan@hotmail.com+86 13636331167

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Mar 4, 2026