postpartum hemorrhage
Conditions
Interventions
dopamine:accept the dopamine treatment (DA group), which could be increased to a maximum dose of 20ug/kg/min.
noradrenaline:accept the norepinephrine treatment (NE Group) randomly, which could be increased rapidly to a maximum dose of 0.20ug/kg/min
Sponsors
ICU, Beijing Tiantan Hospital, Capital Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Postpartum patients older than 18 years old; 2. Patients who conform to the diagnostic criteria of postpartum hemorrhage and after actively etiological treatment and adequate fluid resuscitation hemodynamics is still unstable also need vasoactive drugs; 3. Patients who are given mechanical ventilation; 4. Patents in the ICU; 5. Patients with PiCCO monitoring.
Exclusion criteria
Exclusion criteria: 1. Patients who refuse to sign the informed consent or who have signed the informed consent but quit in the research process; 2. Patients with serious heart diseases such as: cardiomyopathy and congenital heart disease; 3. Patients with primary pulmonary hypertension; 4. Patients with pregnancy associated with kidney failure; 5. Patients administered with dopamine or norepinephrine for less than 6 hours, while the combination of vasoactive drugs or surgery treatment is needed; 6. Patients with missed important data. Patients who fail to set and maintain a central venous catheter as planned, or whose Picco monitoring or blood gas examination has not been conducted.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| stroke volume;vascular resistance index (SVRI);global end diastolic volume index (GEDI);the duration of ventilatory support; | — |
Secondary
| Measure | Time frame |
|---|---|
| lactic acide; | — |
Countries
China
Contacts
Public ContactJianxin Zhou
Daxing Teaching Hospital of Capital Medical University
Outcome results
None listed