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Efficacy of a new dentifrice containing a novel bioactive glass-ceramic for dentin hypersensitivity: a double-blind randomized-controlled trial in adults in China

Efficacy of a new dentifrice containing a novel bioactive glass-ceramic for dentin hypersensitivity: a double-blind randomized-controlled trial in adults in China

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-13003896
Enrollment
Unknown
Registered
2013-11-26
Start date
2013-05-14
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dentin Hypersensitivity

Interventions

test group:the new dentifrice formulation containing 7.5% HX-BGC, a new bioactive glass-ceramic, in a silica base
control group:control dentifrice contained same grinding material as experimental dentifrice but without any HX-BGC

Sponsors

Sichuan University, West China Hospital of Stomatology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria were hypersensitive area on facial surfaces of the teeth (incisors, cuspids and bicuspids with exposed cervical dentine) with at least two nonadjacent teeth scoring two or three at the airblast sensitivity test (Schiff Cold Air Scale) and scoring 10g or 20g at the tactile sensitivity test; good periodontal health (no probing depth >4mm) with no other conditions that might explain their apparent DH; good physical health; age between 18 and 70 years; and provision of written informed consent.

Exclusion criteria

Exclusion criteria: Exclusion criteria were chipped teeth, defective restorations, fractured undisplaced cuspids, deep dental caries or large restorations showing pulpal response, deep periodontal pockets, orthodontic appliances, dentures or bridgework that would interfere with the evaluation of hypersensitivity; progressive periodontitis; hypersensitive teeth with a mobility >1; periodontal treatment, including surgery, within the previous 6 months; patient who had used any other anti-hypersensitivity dentifrice or taken part in any other clinical trial; ongoing treatment for tooth hypersensitivity; gregnancy of lactation; ongoing treatment with antibiotics and/or anti-inflammatory drugs; use of a pace-maker; uncontrolled metabolic diseases; major psychiatric disorder; and alcohol or drug abuse.

Design outcomes

Primary

MeasureTime frame
Airblast test (Schiff);Tactile test (Yeaple);

Countries

China

Contacts

Public ContactDeyu Hu

Sichuan University, West China School of Stomatology

hudeyu@vip.sina.com+86 13908034990

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026