burn
Conditions
Interventions
5-1:nutrition support (calorie/fat/glucose)
5-2:nutrition therapy and metabolic control (glutamine/fish oil)
5-3:recombinant human growth hormone treatment
Sponsors
Third Military Medical University,PLA
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 65 years old; 2. TBSA 30% to 80%; 3. thermal burn patients.
Exclusion criteria
Exclusion criteria: 1. The patient has serious heart, liver, kidney or hematopoietic system dysfunction before the burn injury (the cardiac function>=III level, with moderate or severe cardiovascular disease objective inspection basis; Total bilirubin>=33umol/L; Creatinine>=171µmol/L; 24h urine=<500ml; Platelet<100x10^9/L); 2. the patient has severe asthma or chronic respiratory disease; 3. The patient has severe gastrointestinal bleeding, with chronic gastrointestinal diseases, or used to have the gastrointestinal surgery on admission; 4. With shock or severe inhalation injury; 5. Using glucocorticoid treatment due to other diseases; 6. Using immunosuppressant treatment due to other diseases; 7. Expected survival time less than 24 hours; 8. Pregnancy or breast-feeding women; 9. Suffering from a mental illness, without self-control and clear express, or other mental illnesses; 10. Malignant tumor patients; 11. Don't want to sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 24 hours urine nitrogen discharge;.Intestinal permeability changes (L/M);case fatality;Visceral complications rate;sepsis rate;dates of wound healing;dates of 1% wound healin; | — |
Secondary
| Measure | Time frame |
|---|---|
| tissue oxygen metabolis; | — |
Countries
China
Contacts
Public ContactYuesheng Huang
The First Affiliated Hospital of Third Military Medical University
Outcome results
None listed