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A Randomized, Controlled Study of Long-term Oral N-acetylcysteine in Patients with Bronchiectasis

Effect of N-acetylcysteine on Outcomes in Stable Bronchiectasis: A Randomised Controlled Study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-13003792
Enrollment
Unknown
Registered
2013-09-24
Start date
2013-12-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bronchiectasis

Interventions

Experimental Group:Oral N-acetylcysteine
Control Group:Oral placebo

Sponsors

Qilu Hospital of Shandong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Male or female study subjects aged 18 to 80 years; 2. Confirmed diagnosis of idiopathic bronchiectasis or postinfectious bronchiectasis; 3. Stable Bronchiectasis; 4. One month later after the acute exacerbation of bronchiectasis; 5. There are more than 2 times exacerbations of bronchiectasis during one year before enrollment.

Exclusion criteria

Exclusion criteria: 1. Bronchiectasis due to special causes; 2. Smokers; 3. Are associated with bronchial asthma; 4. Have any serious or active medical or psychiatric illness.

Design outcomes

Primary

MeasureTime frame
Acute exacerbations;Leicester Cough Questionnaire;ST. George's Respiratory Questionnaire;Volume of sputum;The nature of sputum;The content of bacterial in sputum;—

Secondary

MeasureTime frame
Lung function;—

Countries

China

Contacts

Public ContactLi Yu

Shandong University School of Medicine

qlliyu@163.com+86 13791122770

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026