Lumbar spinal stenosis and/or lumbar intervertebral disc herniation and/or Gastrointestinal Tumor
Conditions
Interventions
TIVA group(orthopedics):TIVA aesthesia
Intravenous-inhalation anesthesia group(orthopedics) :Intravenous-inhalation anesthesia
TIVA group (general surgery):TIVA
Intravenous-inhalation anesthesia group (general surgery):Intravenous-inhalation anesthesia
Sponsors
Department of Anesthesia, Third Hospital, Peking University
Eligibility
Sex/Gender
All
Age
60 Years to 90 Years
Inclusion criteria
Inclusion criteria: Older than 60 years and younger than 90 years of age, both genders, no race limitation; Receiving general anesthesia for elective abdominal or lumbar spine surgery, expected operation time longer than 2 hours; Agreed to participate in this study and signed an informed consent form.
Exclusion criteria
Exclusion criteria: Refused to participate in the study; A history of schizophrenia or epilepsy, Parkinson's medical history; due to severe dementia, language barriers, coma, end-stage disease, etc. can not be completed preoperative evaluation; Within 3 months before surgery had myocardial infarction; Severe heart, liver, kidney dysfunction: preoperative ASA classification higher than IV grade; serum creatinine more than 442 umol/L, with or without serum potassium more than 6.5 mmol/L, or clinician considers it necessary to line renal replacement therapy; Child -Pugh grade C; Researchers believe the attending physician or the presence of other conditions should not participate in this study; Allergic to the study medicines.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Perioperative cerebral functional status of patient;Intraoperative Doppler monitoring of cerebral blood flow;Cortisol;IL-6; | — |
Contacts
Public ContactXiangyang Guo
Department of Anesthesia, Third Hospital, Peking University
Outcome results
None listed