gastric cancer
Conditions
Interventions
A:laparoscopic D2 lymphadenetomy
B:laparoscopic D2 lymphadenetomy plus complete mesogastrium excision (D2+CME)
Sponsors
Department of Gastrointestinal Surgery, Tongji Hospital, Tongji Medical College in Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Preoperative endoscopy and biopsy confirmed gastric adenocarcinoma; 2. potentially resectable disease by preoperative staging assessment, including UICC cTNM stage I-IIIa (cT1N0M0-cT3N1M0, except cT4N0M0); 3. Aged from 18 yrs to 75 yrs; no limitation to gender; BMI no more than 30 kg/m^2; WHO performance scale less than 2 score; 4. Informed consent obtained from patients or their appointed agent.
Exclusion criteria
Exclusion criteria: 1. Patients treated with neoadjuvant chemotherapy or radiation therapy; 2. Patients with history of upper abdominal surgery; 3. With other severe comorbidities and cannot tolerate laparoscopic surgery, such as severe heart and lung diseases, heart function below clinical stage 2, pulmonary infection, moderate to severe COPD, chronic bronchitis, severe diabetes and / or renal insufficiency, severe hepatitis and / or function below the rank of CHILD B grade, and severe malnutrition, etc; 4. Patients suffering from malignant diseases before the study or with other gastric malignant diseases, such as lymphoma and stromal tumors, etc.; 5. Pregnant woman and woman during lactation; 6. Patients with mental sickness; 7. The patient compliance is bad or the researcher expect there will not be good patient compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 3 and 5-year survival rate;Complications;blood loss during operation;Operation time;The number of lymph node dissection;Intestinal recovery exhaust time;Positive rate of cancer cells from intraperitoneal; | — |
Countries
China
Contacts
Public ContactJianping Gong
Department of Gastrointestinal Surgery, Tongji Hospital, Wuhan, Hubei
Outcome results
None listed