coronary heart disease
Conditions
Interventions
Treatment group:Rosuvastatin+Berberine
Control group:Rosuvastatin
Sponsors
Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Eligibility
Sex/Gender
All
Age
20 Years to 90 Years
Inclusion criteria
Inclusion criteria: By coronary angiography for the diagnosis of coronary heart disease (the main branch stenosis = 50% and <70%) of patients with stable angina
Exclusion criteria
Exclusion criteria: 1. Exclude the cause of elevated CRP diseases (such as the recent infection, trauma, rheumatic activity, etc.)and significant liver and kidney dysfunction or recent hepatitis persons; 2. Concomitant diseases, such as cancer, thyroid disease, tuberculosis or taking hormones; 3. The combined effect on hemodynamics in patients with valvular heart disease; 4. Drug side effects or unacceptable IVUS follow-up; 5. Associated with mental illness, such as depression, mania, and not long-term cooperation mental disorders; 6. Alcoholism or drug addicts.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Triglycerides;Cholesterol;High-density lipoprotein;Low-density lipoprotein;Serum creatinine;hsCRP;MMP-9;ICAM-1;VCAM-1;NF-kB;p38;AMP;ERK;PPAR; | — |
Countries
China
Contacts
Public ContactMeng Shu
Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
Outcome results
None listed