Effect of KangBaiyannian decoction combined with low dose chemotherapy in the treatment of elderly patients with acute myeloid leukemia: a multicenter randomized controlled clinical study

Effect of KangBaiyannian decoction combined with low dose chemotherapy in the treatment of elderly patients with acute myeloid leukemia

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-13003671

Enrollment

Unknown

Registered

2013-10-08

Start date

2013-12-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

leukemia

Interventions

Control group:low dose chemotherapy

Experimental:KangBaiyannian decoction + low dose chemotherapy

Eligibility

Sex/Gender

All

Age

60 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. The diagnosis of acute myeloid leukemia (including primary, chemotherapy without remission); 2. Older than 60 years old; 3. Tolerant to chemotherapy (ECOG score <=2, with no severe organ dysfunction).

Exclusion criteria

Exclusion criteria: 1. Exclude other diseases with abnormal proliferation of primitive cells, including myelodysplastic syndrome, chronic leukemia, et al; 2. The heterozygosity and mixed leukemia; 3. Patients with severe heart, brain, liver, kidney and mental disease, with the ECOG score > 2; 4. Patients cannot take Chinese traditional medicine or with allergic.

Design outcomes

Primary

Measure	Time frame
TCM syndrome score;remission rate;Passing rate of chemotherapy;myelograph;	—

Secondary

Measure	Time frame
mutation and resistance gene expression;immnue index and tumor burde;	—

Countries

China

Contacts

Public ContactShen Yiping

Zhejiang Provincial Hospital of Traditional Chinese Medicine

shenyp_@126.com+86 13819178391

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026