Angina pectoris combined with arterial atherosclerotic cerebral infarction
Conditions
Interventions
Experimental group:He Xue Tong Mai particles
Control group:Placebo
Sponsors
Affiliated Hospital of Liaoning University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
35 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Comply with the diagnostic criteria of angina pectoris and atherosclerotic cerebral infarction (2 weeks -8 weeks) at the same time; 2. Comply with the diagnostic criteria of Phlegm and blood stenosis syndrome of angina pectoris combined with arterial atherosclerotic cerebral infarction; 3. The score of U.S. National Institutes of Health Stroke Scale (NIHSS) was >=5 points; 4. Aged from 35 to 85; Signed Informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with acute coronary syndrome (ST-segment elevation myocardial infarction, non-ST-segment elevation myocardial infarction, unstable angina, silent myocardial ischemia and ischemic cardiomyopathy; 2. Patients with rheumatic heart disease, hyperthyroidism, heart disease, myocarditis, cardiomyopathy, hypertension induced heart disease and other non-coronary atherosclerotic heart disease and cardiac neurosis; 3. In addition to atherosclerotic cerebral infarction of other reasons, such as arteritis, brain tumor, brain trauma, brain parasites, metabolic disorders, polycythemia vera, thromboembolism, intracranial vascular malformations, cerebral amyloidosis, etc; 4. Cerebral embolism, cerebral hemorrhage, transient ischemic attacks, lacunar infarction; 5. Patients associated with serious primary diseases of liver, kidney, hematopoietic system, malignant tumors, gastrointestinal bleeding and that were not expected to complete the trial; 6. Pregnant, breast-feeding women and Allergic people; 7. Patients with dementia, mental illness; 8. Patient with the rate of Modified Rankin Scale (MRS) of five (including unconsciousness) or Kubota water test >= 4 grade; 9. Canadian Cardiovascular Society (CCS) angina severity rating of 4; 10. People who participate in other clinical trials in two weeks; 11. Patients now use Chinese medicine which can promote blood circulation and dispel phlegm; Patient refused to sign the informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Syndromes (including clinical symptoms, signs, tongue, pulse);Angina Credits;Seattle angina questionnaire;NIH Stroke Scale;SS-QOL;ADL;Modified Rankin Scale; | — |
Countries
China
Contacts
Public ContactGuanlin Yang
Liaoning University of Traditional Chinese Medicine
Outcome results
None listed