mental fatigue
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. aged between 18 to 35 years; 2. healthy and normal sleep; 3. No coffee, tea, tobacco and alcohol dependence. Not take coffee, tea, wine or other psychoactive drugs 24h before examination; 4. normal vision or normal corrected vision; 5. right-handed.
Exclusion criteria
Exclusion criteria: 1. with severe neurological disease affect cognition; 2. with other psychiatric diseases; 3. with systemic diseases (such as arrhythmia, diabetes, organ dysfunction, hypertension, an-emia, thyroid dysfunction, malnutrition, infection and et al); 4. had a history of seizure. 5. drug or alcohol abuse or dependence. 6. vital signs or physical examination or neurological examination revealed abnormal. 7. routine use hypnotics for more than 2 times per week 30 days before screening. 8. long-term administration of coffee. 9. with sleep disorders in recent one month. 10. hearing impairment or severe visual impairment. 11. participating in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ambulatory electroencephalograph; | — |
Secondary
| Measure | Time frame |
|---|---|
| Stanford Sleepiness Scale;examination of auditory working-memory vigilance task;heart rate; | — |
Countries
China
Contacts
Department of Neurology, Xinqiao Hospital, Third Military Medical University