preterm infants with brain retardation
Conditions
Interventions
treatment:rat nerve growth factor
Control:Rutine treatment
Sponsors
The First Affiliated Hospital Of Jinan University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Male or female premature gestational age less than 32 weeks, weight less than 1.5kg; 2. premature who agree to accept examinations of electroencephalogram ,brainstem auditory evoked and nuclear magnetic resonance during the period of observation; 3. premature who agree to accept tests of Gesell and PEABODY; 4. premature who have read subjects informed form and agreed to sign written informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients who are currently attending other clinical trials or attended others clinical trials in a month; 2. Patients who are taking other nervous system drugs treatment; 3. Patients with serious liver and kidney disease,blood system diseases ,autoimmune diseases , chronic serious infection ,other congenital disease and so on; 4. Patients who are unsuitable for the trail,suggested by researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nuclear magnetic resonance diffusion tensor imagine;PEABODY developmental motor scale;electroencephalogram;Gesell scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| brain stem auditory evoked potentia; | — |
Countries
China
Contacts
Public ContactLiu Guosheng
Outcome results
None listed