Esophageal cancer
Conditions
Interventions
Study group:All-in-one bags,fat emulsion is olive-oil-based lipid emulsion (ClinOleic)
control group:All-in-one bags,fat emulsion is LCT/MCT fat emulsion(Lipofundin)
Sponsors
Tangdu Hospital, The fourth military medical university
Eligibility
Sex/Gender
All
Age
35 Years to 70 Years
Inclusion criteria
Inclusion criteria: All patients enrolled in this study are those need radical esophagectomy for esophageal carcinoma, either male or female, the age range from 35 to 70 years old. The informed consent form and ethic committee are necessary before the enrollment.
Exclusion criteria
Exclusion criteria: (1) the patients have taken part in another drug cilincial trial in four weeks; (2) lipid emmusion have been infused for malnutrition in one week; (3) life expectancy less than seven days; (4) contraindication for parenteral nutrition (disturbance of blood coagulation ,unrightable Metabolic disease); (5) known in pregnancy or breastfeeding; (6) patients are potential uncooperative or dont obey the reseach protocol; (7) severe cardiopulmonary insufficiency; (8) severe dyslipdemia (Triglyceride or cholesterol levels are more than 2 times of the upper limit of normal); (9) liver dysfunction (AST level are more than 3 times the upper limit of normal, Severe cholestasis or Conjugated bilirubin level of are more than 2 times the upper limit of normal); (10) Chronic renal failure (the level of BUN and Creatinine exceed 2 times of the upper limit of normal); (11) be allergic to any ingredients or accessories of lipid emmusion(eg. Egg or soybean protein); (12) long history of corticosteroids and immunosuppressive agents; (13) History of preoperative radiotherapy or chemotherapy; (14) Long history of autoimmune disease (Rheumatoid arthritis HIV, SLE et al); (15) disease appears in three months, which have bad effect on the immune system,such as chronic infection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| clinical outcome;immune function;Nutrition parameter;liver and renal function tests;blood glucose, cholesterol and triglycerides; | — |
Countries
China
Contacts
Public ContactXiaolong Yan
Tangdu Hospital, The fourth military medical university,
Outcome results
None listed