Nonalcoholic fatty liver disease
Conditions
Interventions
Two groups:Lifestyle intervention with modification of diet, physical activity and behaviour patterns versus conventional care
Sponsors
Nil
Eligibility
Sex/Gender
Male
Age
14 Years to 18 Years
Inclusion criteria
Inclusion criteria: Post-pubertal Chinese adolescents aged 14 -18 years with primary obesity attending the Obesity and Lipid Disorder Clinic in Prince of Wales Hospital. Signed informed consent by parents and assent by children.
Exclusion criteria
Exclusion criteria: Hepatic viral infection Daily usage of alcohol, from parental or self-report BMI below 95th centile of local reference Using steatogenic and /or anti-diabetic drugs Concurrent participation in any clinical trial, dietary intervention or weight loss program Concomitant intake of a weight reducing agent Any chronic medical illness Unwillingness to attend regular follow up appointments as part of the intervention programme.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the degree of change of intrahepatic triglyceride ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Anthropometric measurements: height, weight, body ;Blood tests: plasma fasting glucose, lipid profile; | — |
Countries
China
Contacts
Public ContactDorothy Chan
Outcome results
None listed