HBV-related liver failure
Conditions
Interventions
Sponsors
Department of transfusion, Daping Hospital, Third Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Diagnosed with liver failure caused by hepatitis B virus; 2. Both male and female between 18-65 years of ages; 3. Patients voluntarily signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Liver failure caused by other reasons, such as autoimmune diseases, alcohol, drug and so on; 2. Allergies or patients have an allergy to plasma; 3. Chronic liver failure, CLF; 4. Prothrombin time activity, PTA<=20%; 5. Active bleeding or bleeding tendency obviously, DIC, shock and hemodynamic instability; 6. Previous history of abnormal coagulation function or related blood system disease (e.g. hemophilia, leukemia); 7. Tumor on ultrasonography, CT or MRI examination 8. primary non function liver graft or graft dysfunction 9. Severe problems in other vital organs(e.g. the heart, renal or lungs) 10. Patients with mental disorder or disease; 11. Pregnant or breast-feeding women; 12. Patients already received other artificial liver support system treatment before the study; 13. Participate in other clinical trials within 3 month before the study; 14. Other cases which researchers believe that can not enroll.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mortality; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cost of hospitalization;The occurrence and time of complications;Liver function evaluation using MELD score;Improve biochemical indexes;The clinical symptom improvement;Length of stay;Quality of life;The incidence of adverse reaction; | — |
Contacts
Public ContactAiqing Wen
Outcome results
None listed