Sterility
Conditions
Interventions
PGS:single thawed blastcyst transfer after preimplantation genetic scanning
control:signle blastcyst transfer after frozen
Sponsors
Reproductive and genetic Hospital of Citic- Xiangya
Eligibility
Sex/Gender
Female
Age
20 Years to 35 Years
Inclusion criteria
Inclusion criteria: 1. Age <=35y, BMI <=27kg/m2; 2. Polycystic ovary syndrome (PCOS) patients; 3. the first or second treatment cycle; 4. bilateral ovaries, FSH< 8miu/ml; 5. high risk of OHSS needs to cancel the fresh embryo transfer; 6. signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Endometriosis disease; 2. unilateral or bilateral hydrosalpinx (B ultrasound examination); 3. uterine malformation, multiple uterine myoma, uterine intramural myoma >3cm, submucous myoma; 4. intrauterine adhesions history, history of uterine cavity effusion of unknown cause; 5. abnormal childbearing history, more than two times of unexplained abortion; 6. other reasons need to preimplantation genetic diagnosis (PGD), preimplantation genetic scanning (PGS); 7. the number of good quality embryos on day three of oocyte retrieval (6 cell grade II) less than five; 8. on the day of oocyte retrieval, spermatozoon is only C grade (WHO); 9. the previous history of abnormal thyroid function; 10. history of hypertension, systolic pressure >=150mmHg, DBP >=90mmHg; 11. previous or ongoing epilepsy, diabetes, cardiovascular disease, gastrointestinal diseases, liver disease, kidney disease, lung disease; 12. the woman of smoking, alcoholism, drug addiction; 13. cervical biopsy showed CIN I level and above.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| live birth rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| pregnancy rate;implantation rate; | — |
Countries
China
Contacts
Public ContactLin Ge
Outcome results
None listed