Depression
Conditions
Interventions
Two groups:Behavior An aerobic exercise programme consists of jogging, fast walking and cycling, as adjunct treatment to treatment as usual for 12 weeks versus Treatment as usual in the psychiatric ou
Sponsors
Dr. CHEUNG Lap Kei, the principal investigator, who is a resident in the Department of Psychiatry, Tai Po Hospital
Eligibility
Sex/Gender
Male
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients with major depressive disorder as diagnosed by the Structured Clinical Interview for DSM-IV with the Hamilton Depression Rating Scale score >= 14 and self reported to be physically inactive at the time of the study (with <2 times of exercise per week)
Exclusion criteria
Exclusion criteria: Patients will be excluded if they are 1) suffering from depressive symptoms in other mental illnesses e.g. bipolar affective disorder, psychotic disorders including schizophrenia and schizoaffective disorder, and obsessive-compulsive disorder, 2) taking substance(s), and 3) suffering from physical conditions that prevent them from doing jogging, cycling or brisk walking. These conditions include untreated hypertension, ischaemic heart disease, cardiomyopathy, arrhythmia, moderate to severe respiratory diseases, history of cerebrovascular accident, severe liver and renal problems, musculoskeletal conditions that hinder the patients from doing aerobic exercise, and any other physical condition or severity of a physical condition that in the opinion of the patient’s physician or the principal investigator that the patient is unfit to participate in the exercise programme. And for women, patients who are currently pregnant or who plan to get pregnant in the next 3 months will also be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Depression severity to be measured at baseline and 12 weeks by Hamilton Depression Rating Scale.; | — |
Secondary
| Measure | Time frame |
|---|---|
| somatic distress (by PHQ-15);anxiety (by STAI);quality of life (by SF-36);sleep quality (by Pittsburg Sleep Quality Index);certain cognitive performance (the Trail-making test, the Hong Kong List Learning Test, and the verbal fluency test);body composition (body weight and waist circumference); | — |
Contacts
Public ContactDr. CHEUNG LAP KEI
Outcome results
None listed