methamphetamine dependence
Conditions
Interventions
group A:methylphenidate SR
group B:Placebo
Sponsors
Ningbo Addiction Research and Treatment Center
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: Subjects will be recruited from inpatient department in Ningbo Addiction and Treatment Center, and meet the following criteria: 1. Treatment-seeking subjects with age between 18 years and 55 years, both genders are eligible for study; 2. Meet the DSM-IV diagnosis of methamphetamine dependence in the latest year; 3. Be willing and able to comply with study procedures, be able to verbalize and understand consent forms and provide written informed consent.
Exclusion criteria
Exclusion criteria: 1. currently having neurological disorders including epilepsy, brain tumor, multiple sclerosis, Gilles de la Tourette syndrome, anxiety disorder and psychotic disorders; 2. Diagnosis of Gilles de la Tourette syndrome in the immediate family; 3. Current dependence on substances other than nicotine or amphetamine type stimulants; 4. Having contraindications such as pregnancy, glaucoma, cardiomyopathies and severe arrhythmia; 5. Having conditions that may pre-terminate the trial, such as liver dysfunction, kidney dysfunction, anemia, leucocytopenia, and thrombocytopenia; 6. Other conditions that makes the subjects unlikely to finish the follow-up, e.g., traffic inconvenience.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| time of abstinence;the reduction of methamphetamine use; | — |
Secondary
| Measure | Time frame |
|---|---|
| retention;Obsessive compulisive drug use scale;desires for drug questionnaire;Pittsburgh sleep quality index; | — |
Countries
China
Contacts
Public ContactWenhua ZHOU
Outcome results
None listed