Pain management after craniotomy
Conditions
Interventions
Group B:Scalp nerve block with 20ml of 0.25% ropivacaine before skin incision and scalp nerve block in the same position with same volume of 0.9% saline after surgery while patients are not awake from
Group A:Scalp nerve block with 20ml of 0.9% saline before skin incision and scalp nerve block in the same position with same volume of 0.25% ropivacaine after surgery while patients are not awake from
Group BA:Scalp nerve block with 20ml of 0.25% ropivacine both before skin incision and after surgery while patients are not awake from anesthesia
Group C:Scalp nerve block with 20ml of 0.9% saline both before skin incision and after surgery while patients are not awake from anesthesia
Sponsors
Tongji Hospital of Tongji Medical college of Huazhong University of Science and Technology,Deprtment of Anesthesiology
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: PatientsASA physical status I-II; aged 18 to 60 year; weighted from 45 to 75 kg; after informed consent; can understand and correctly use Visual Analogue Scale to pain assessment,scheduled to craniotomy either for brain tumors or cerebral vascular malformations,operation time lasts 3-4 hours, under Total Intravenous Anesthesia with BIS monitoring, got conscienseness (GCS>=15) and extubated within half an hour afer surgery, are erolled.
Exclusion criteria
Exclusion criteria: pregnancy and breast-feeding women and patients with serious hepatic or renal dysfunction, ASA physical status >=III, cannot understand or correctly use VAS to pain assessment,allergical to either local anesthetic or general anesthetic,
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS pain score;other pain-telated drugs; | — |
Secondary
| Measure | Time frame |
|---|---|
| PONV score;GCS pain score;Rasmay sedation score after surgery of 30 minutes and 2?4?6?12?24?48 hours respectively;occurence of shivering;SpO2;occurence of dizziness;occurence of itching;cumulative rescue analgesics;cumulative rescue sedative drugs; | — |
Countries
China
Contacts
Public ContactPeng Wang
Outcome results
None listed