COPD
Conditions
Interventions
oxygen-driven nebulization:oxygen-driven nebulization
classical ultrasonic nebulization:classical ultrasonic nebulization
ultrasonic nebulization with warming and oxygen:ultrasonic nebulization with warming and oxygen
Sponsors
First Affiliated Hospital of Guangzhou Medical University
Eligibility
Sex/Gender
All
Age
50 Years to 85 Years
Inclusion criteria
Inclusion criteria: Between December 2010 and November 2011 hospitalized patients with AECOPD diagnosed according to the Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines 2009 at the First Affiliated Hospital of Guangzhou Medical University, will be recruited for the present study.
Exclusion criteria
Exclusion criteria: (1) concomitant bronchial asthma or hemoptysis; (2) a history of chest surgery or active bleeding during the previous 3 months; (3) inability to complete a pulmonary function test (PFT) due to certain conditions (pulmonary bullae, dyspnea, pulmonary embolism necessitating bed rest, or coronary heart disease), and (4) infectious diseases, mental disorders, severe cognitive impairment, or other conditions that may prevent the patient from cooperating with the investigators.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| nebulization rate; | — |
Primary
| Measure | Time frame |
|---|---|
| frequency of cough;time to first expectoration;FVC;FEV1;PEF;Peripheral oxygen saturation (SpO2);heart rate (HR);respiratory rate (RR);dyspnea;chest tightness;patient comfort about the nebulization;Temperature of mouthpiece aerosol; | — |
Countries
China
Contacts
Public ContactZeguang Zheng
Outcome results
None listed