influenza-like illness in children
Conditions
Interventions
experimental group:Kanggan Granule
control group:Ribavirin Granule
Sponsors
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
1 Years to 14 Years
Inclusion criteria
Inclusion criteria: 1. Children meeting the Western diagnostic criteria of influenza-like illness; 2. Children meeting the criteria of syndrome of wind-heat invading superficial part; 3. Aged 1 to 14 years; 4. With pre-diagnostic 24h maximum axillary temperature<=38.5 degree; 5. Disease course <=24 hours; 6. Parents or guardians signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Blood WBC> 10*10^9/L, or the percentage of neutrophilic granulocyte>the upper limit of normal; 2. Having taken other drugs to treat the studied disease before 24 hours prior to this treatment; 3. Patients with severe malnutrition, rickets as well as combined severe primary diseases of heart, brain, liver, kidney and hematopoietic systems etc; 4. Liver function AST, ALT> 1.5N (N is upper limit of normal); renal function (Cr)>the upper limit of normal; 5. Allergic patients (two or more kinds of food or drug allergies) or those who are allergic to the test drug; 6. Patients not suitable for inclusion judged by researchers or influencing participation or completion of the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| fever clearance time;clinical recovery time; | — |
Secondary
| Measure | Time frame |
|---|---|
| AUC of main symptoms (fever, headache, nasal congestion, runny nose, sore throat);effect of TCM syndrom; | — |
Countries
China
Contacts
Public ContactSiyuan Hu
Outcome results
None listed