recurrent respiratory infections in children
Conditions
Interventions
experimental group:Xuhanting Granular plus Yupingfeng Granular placebo
control group:Yupingfeng Granular plus Xuhanting Granular placebo
placebo group:Xuhanting Granular plus Yupingfeng Granular placebo
Sponsors
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
1 Years to 6 Years
Inclusion criteria
Inclusion criteria: 1. Children meeting the Western diagnostic criteria of recurrent respiratory infections; 2. Children of non-acute phase infection, or 1week or more after acute infection recovery; 3. Children meeting the criteria of syndrome of Qi and Yin deficiency; 4. Aged 1.5 to 6 years; 5. Disease course >=1 year; 6. Parents or guardians signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Respiratory infections caused by basic disease of primary immunodeficiency disease, acquired immune deficiency syndrome (ADRS), congenital airway malformations, congenital heart disease, gastroesophageal reflux disease (GERD), and lung abnormalities etc; 2. Having used immunosuppressant or immune enhancer, as well as taken other drugs of recurrent respiratory tract infections in the past 1 year; 3. Patients with severe malnutrition, rickets as well as combined severe primary diseases of heart, brain, liver, kidney and hematopoietic systems etc; 4. Allergic patients (two or more kinds of food or drug allergies) or those who are allergic to the test drug; 5. Patients not suitable for inclusion, or influencing participation or completion of the study judged by researchers; 6. Patients participated in other clinical trials in the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the amount of sweat per day (spontaneous sweating,;Compliance rate of recurrent respiratory tract infection; | — |
Secondary
| Measure | Time frame |
|---|---|
| effect of TCM syndrome;effect of sigle symptoms;effect of immune parameters (serum globulin: IgA, IgG, IgM); | — |
Countries
China
Contacts
Public ContactSiyuan Hu
Outcome results
None listed