hypotension during cesarean delivery
Conditions
Interventions
Group S:Five min prior to spinal anesthesia, patients were intravenously injected with 5 ml saline
Group O2:Five min prior to spinal anesthesia, patients were intravenously injected with2mg ondansetron (diluted in 5 ml physiological saline)
Group O4:Five min prior to spinal anesthesia, patients were intravenously injected with4mg ondansetron (diluted in 5 ml physiological saline)
Group O6:Five min prior to spinal anesthesia, patients were intravenously injected with6mg ondansetron (diluted in 5 ml physiological saline)
Group O8:Five min prior to spinal anesthesia, patients were intravenously injected with8mg ondansetron (diluted in 5 ml physiological saline)
Sponsors
Wuxi Maternity and Child Health Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: The patients were aged 18–35 years, all were at 37–42 weeks gestation, and all were classified as ASA grade I–II. All women had normal prenatal examinations, normal liver and renal function prior to caesarean delivery, and had no medical history of heart or lung diseases. In addition, fetal screening revealed no abnormalities.
Exclusion criteria
Exclusion criteria: Patients who met the following criteria were excluded from the study: 1. women with hypertension (systolic blood pressure > 140 mm Hg or diastolic blood pressure > 90 mm Hg); 2. women with cardiovascular and/or cerebrovascular diseases; 3. women with abnormal fetus development; 4. women with contraindications for intraspinal anesthesia or endocrine disorders such as diabetes mellitus; 5. women who were recently administered 5-hydroxytryptamine (5-HT) reuptake inhibitors or drugs for the treatment of migraines.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood pressure;Heart Rate;SpO2;Occurrence of hypotension;Occurrence of bradycardia;Occurrence of nausea;Occurrence of vomiting;Umbilical blood gas analysis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Block height during spinal anesthesis; | — |
Countries
China
Contacts
Public ContactMeng Wang
Outcome results
None listed