Helicobacter Pylori infection
Conditions
Interventions
A:PPI+ bismuth+amoxicillin,+clarithromycin
B:PPI+ bismuth+amoxicillin+ levofloxacin
C:PPI+amoxicillin+ levofloxacin
Sponsors
First Affiliated Hospital of Nanjing Medical University
Eligibility
Sex/Gender
All
Age
20 Years to 65 Years
Inclusion criteria
Inclusion criteria: Patients were eligible for recruitment if they were aged from 20 to 65 years old and were dignosed as duodenal ulcer or chronic gastritis.Meantime they should have documented H pylori infection and never have previous eradication treatment for H pylori.
Exclusion criteria
Exclusion criteria: (1) use of antibiotics, bismuth, H2RA and PPI, anticoagulant drugs in the past 4 weeks: (2) histor y of gastrectomy,gastric malignancy, including adenocarcinoma and lymphoma; (3) active upper gastrointestinal bleeding within the previous 1 week; (4) pregnant or lactating women; (5) At the same time there are other serious diseases such as severe liver disease, heart disease (including block, chronic heart failure), kidney disease, cerebrovascular disease, cancer and alcoholism disorders affecting the evaluation of this study; (6) allergic reaction to the drug used in this study; (7) during treatment need to take the metal preparations (metal preparations may chelation with levofloxacin, except bismuth); (8) participate in other drug studies in the past 3 months before: (9) the patient who can not properly express their own complaints, such as psychosis, severe neurosis, not collaborators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| eradication rate; | — |
Contacts
Public ContactGuoxin Zhang
Outcome results
None listed