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Effect of dachengqi decoction combined probiotic on gastrointestinal dysfunction after severe trauma of clinical study

Effect of dachengqi decoction combined probiotic on gastrointestinal dysfunction after severe trauma of clinical study

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-13003248
Enrollment
Unknown
Registered
2013-06-04
Start date
2013-05-08
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

severe trauma

Interventions

A:Early enteral nutrition for 21 days
B:Early entaral nutrition for 21 days plus bifico of 14 days
C:Early entaral nutrition for 21 days plus bifico of 14 days plus dachengqi decoction 3-5days

Sponsors

Nursing Departmen Of The Third Minitary Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. The trauma cases meet a specific criterion that AIS (abbreviated injury scale)>=3 pointsand ISS (injury severity score)>=16points as well; 2. Be recived among 24h,length of hospital stay may be longer and expected to survival time is more than 7 days; 3. GCS score for patients with severe head injury, should be in five to eight points, duration is 12h; 4. Inpatients with ages between 18-65 and no sex limitation; 5. The informed consent is signed, patients and their families have a good compliance.

Exclusion criteria

Exclusion criteria: 1. The case who has the disease of digestive tract,such as gastrointestinal compound injury; gaslrointestinal perforation; intestinal hemorrhage; intestinal ischemic necrosisintestinal fistula and other disease of bowel; 2. The case who has been suffered from hypoproteinemia;infectious diseases;cancer;serious endocrine disease; serious incompetence of liver, heart, lung, kidney and severe immune deficiency; 3. Other diseases turn up during the therapy, and medical treatment accompanied will interfere with clinical observer who investigate the drugs; 4. During the period of chemotherapy, gestation and lactation; 5. The case has accepted other gastrointestinal dysfunction related treatment; 6. The case whose obesity[BMI(Body Mass Index)> 30points] or malnutrition(BMI < 18.5 points); 7. The case can not be implemented enteral nutrition owing to other reasons.

Design outcomes

Primary

MeasureTime frame
D - lactic acid;motilin;proealcitonin;prealbumin;

Countries

China

Contacts

Public ContactZhu Jingci
zhujingci@163.com+86 023-68771156

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026