Coronary artery disease with heart failure
Conditions
Interventions
Treatment group:standard treatment of heart failure+Lu Hong Granule
comparison group:standard treatment of heart failure
Sponsors
Shuguang hospital affiliated to Shanghai university of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: Aged from 18-85 with no sex limitation; diagnosis in coronary artery disease with left ventricular dysfunction; Lu Hong Granule treatment group should with TCM diagosis yang deficient and blood stasis; in class II-IV heart failure diagosis by New York Heart Association.
Exclusion criteria
Exclusion criteria: persistant severe angina (CCS Class IV); undertaking CABG or PCI surgery during the trial; kidney failure with SCr>1.5*ULN; severe liver disease or abnormal in liver biomarks(ALT, AST or TBil>2* ULN); any other severe disease or situation like malignant tumor; undertaking another clinical trial; pregnant woman or preparing to pregnant; researchers think not being suitable to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| all-cause mortality;Nonfatal myocardial infarction;Nonfatal stroke;Intervention or surgery therapy caused by ACS or angina;Worsening heart failure hospitalization;carotid artery ultrasound;cardiac ultrasound;BNP;Cardiac function;TCM symptoms evaluation;Efficacy evaluation; | — |
Secondary
| Measure | Time frame |
|---|---|
| blood routine test;urine routine test;6-minute walk test;Hypersensitivity CRP;blood routine tests;Liver function;Renal function;electrocardiogram;electrolyte;TNI;blood lipids;Quality of life survey;Medication adherence survey;blood glucose; | — |
Countries
China
Contacts
Public ContactWang Xiao-long
Outcome results
None listed