Chronic Obstructive Pulmonary Disease
Conditions
Interventions
Lianhuaqingwen therapy group:based treatments+Lianhuaqingwen capsules
conventional therapy group:based treatments+ placebo
Sponsors
Huashan hospital, Fudan university
Eligibility
Sex/Gender
All
Age
85 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. Aged 50 to 85 years old, gender not limited; 2. COPD was defined according to recent guidelines(GOLD); 3. Deteriorated beyond everyday situationand the need to change the drug treatment; 4. All volunteers signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. With respiratory failure (quiet breathing, the sea level, no oxygen, PaO2 50 mmHg), and have to use mechanical ventilation; 2. Combined serious primary diseases and immunocompromised disorders such as cardiovascular diseases, tumor and autoimmune diseases et al.; psychiatric patients; Pregnancy or breast-feeding women; With severe stomach disease, can't tolerate oral drug therapy; 3. Upper or lower respiratory tract infection in two months before the study; 4. Use traditional Chinese medicine treatment of 36 hours; 5. Have allergy history of medicine composition; 6. Participated in other clinical subjects within three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| COPD assessment test scale;Chinese Medicine Symptom Complex Score scale;GOLD grade; | — |
Secondary
| Measure | Time frame |
|---|---|
| interleutin-8;tumor necrosis factor alpha;interleukin-17;interleukin-23; | — |
Countries
China
Contacts
Public ContactCHEN Xiao-dong
Outcome results
None listed