Effect of dexmedetomidine on remifentanil requirement for inhibiting body movement to skin incision in the same sedative depth

Effect of dexmedetomidine on intraoperative analgesic requirement

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR-TRC-13003216

Enrollment

Unknown

Registered

2013-05-13

Start date

2013-06-01

Completion date

Unknown

Last updated

2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

mammary tumor patients in general anaesthesia

Interventions

1:administrated saline + Propofol

2:propofol and dexmedetomidine 0.5 ug/kg

3:propofol and dexmedetomidine 1.0 ug/kg

Eligibility

Sex/Gender

All

Age

20 Years to 50 Years

Inclusion criteria

Inclusion criteria: ASA grade I or II, aged 20-50 years and body weight index 19-23 kg/m2.

Exclusion criteria

Exclusion criteria: bradycardia, atrioventricular block, neurologic disorder and recent use of psychoactive medication, including alcohol.

Design outcomes

Primary

Measure	Time frame
effect-site concentration of remifentanil pre-incision;	—

Secondary

Measure	Time frame
BIS values 1 min before incision and immediately after the skin incision and 1 min after incision;age and BWI of patient;effect-site concentration of propofol pre-incision;Bispectral index;	—

Countries

China

Contacts

Public ContactDong-hua Shao

13805281211@163.com+86 0511-88915960

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026