tuberculous pleurisy
Conditions
Interventions
intervention group:Isoniazid, rifampicin, ethambutol and pyrazinamide tablets plus prednisolone
Control:Isoniazid, rifampicin, ethambutol and pyrazinamide tablets
Sponsors
Institute of Surgery Research, Daping Hospital, Third Military Medical University, Chongqing, China
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Aged from 18 to 80 years old; Signed written informed consent; Presented with clinical features suggesting pleural tuberculosis; Had not previously received treatment or prophylaxis for tuberculosis; Had not recently received treatment with glucocorticoids; Were not pregnant or breast-feeding.
Exclusion criteria
Exclusion criteria: Failed to complete the screening procedures; Were seropositive for HIV: Had risk factors for serious steroid-related adverse events (a history of diabetes or positive urine glucose, a history or clinical finding of hypertension, or a history of peptic ulcer disease or mental illness); Standard doses of antituberculosis drugs could not be used (as in participants with concurrent liver disease) Psychiatric illness; Alcoholism.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Presence of pleural thickening; | — |
Countries
China
Contacts
Public ContactGuoqiang Cao
Outcome results
None listed