Organ Transplantation
Conditions
Interventions
Bone Marrow cells infusion:donor bone marrow cells infusion
donor bone fragment:donor bone fragment
Bone Marrow cells infusion + donor bone fragment i:Bone Marrow cells infusion + donor bone fragment
Sponsors
Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1, agree to participate in this study and give informed consent;2, age 18-65 years old, both male and female;3, the first time to receive a kidney transplant.
Exclusion criteria
Exclusion criteria: 1. the warm ischemic time>10min; 2. the cold ischemic time>24hours; 3. fail to complete the related examinations; 4. donor and recipient with HBV,HCV,and AIDS; 5. participating any other clinical trial; have been participated any other clinical trial during the past 12 weeks; 6. other situations that should be excluded into this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| serum creatinine;GFR;DGF;rejection diagnosed by clinical data;rejection diagnosed by pathology;infection complications;kidney allograft pathology;bone fragments detection; | — |
Secondary
| Measure | Time frame |
|---|---|
| urine rountine;other complications;ELISPOT;Immuno-Cylex;chimera detection;immunosuppresive regimen;CNI/Rapa concentration;MPA trough level/AUC;HLA matching;complement-dependent cytotoxicity;panel reaction antibody; | — |
Countries
China
Contacts
Public ContactChen Xiaoping
Outcome results
None listed