polycystic ovary syndrome
Conditions
Interventions
fresh embryo transfer group:rFSH/GnRH antagonist ovarian hyperstimulation, oocyte pick-up, fresh embryo transfer, luteal phase support, follow-up
frozen-thawed embryo transfer group:rFSH/GnRH antagonist ovarian hyperstimulation, oocyte pick-up, all embryos cryopreservation, frozen-thawed embryo transfer, luteal phase support, follow-up
Sponsors
Reproductive medical Hospital affiliated to Shandong University
Eligibility
Sex/Gender
Female
Age
20 Years to 34 Years
Inclusion criteria
Inclusion criteria: 1. Women diagnosed as PCOS according to Chinese PCOS diagnosis criteria; 2. Women who have >=1 years history of infertility; 3. Women aged >=20 and 3; 8. Women who are capable of giving informed consent.
Exclusion criteria
Exclusion criteria: 1. Women who underwent unilateral ovariectomy; 2. Women diagnosed as uterus abnormality: malformed uterus (uterus unicornis, septate uterus, duplex uterus, uterus bicomis), adenomyosis, submucous myoma, intrauterine adhesion; 3. Women or their partner with abnormal chromosome karyotype including chromosome polymorphism; 4. Women who have experienced recurrent spontaneous abortion (including biochemical pregnancy abortion) more than 2 times; 5. Women with medical condition that represent contraindication to assisted reproductive technology and/or pregnancy, such as poorly controlled Type I or Type II diabetes; undiagnosed liver disease or dysfunction (based on serum liver enzyme testing); renal disease or abnormal serum renal function; significant anemia; history of deep venous thrombosis, pulmonary embolus, or cerebrovascular accident; uncontrolled hypertension, known symptomatic heart disease; history of or suspected cervical carcinoma, endometrial carcinoma, or breast carcinoma; undiagnosed vaginal bleeding; 6. Women who has developed severe OHSS before oocyte pick-up day; 7. Women with retrieved oocytes number <=3; 8. Women who are unable to comply with the study procedures.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| live birth rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| OHSS incidence;clinical pregnancy rate;pregnancy loss rate;ectopic pregnancy rate;singleton live birth rate;pregnancy complication incidence;Congenital Anomalies rate;Neonatal complication rate; | — |
Countries
China
Contacts
Public ContactZi-jiang Chen
Outcome results
None listed