Tuberculous Pleurisy
Conditions
Interventions
Intervention Group:prednisolone
Control:Placebo
Sponsors
Beijing Chao-Yang Hospital, Capital Medical University,Beijing Institute of Respiratory Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 65 years; 2. Genders Eligible for Study: Both; 3. Signed written informed consent; 4. Presented with clinical features suggesting pleural tuberculosis; 5. Had not previously received treatment or prophylaxis for tuberculosis; 6. Had not recently received treatment with glucocorticoids; 7. Were not pregnant or breast-feeding.
Exclusion criteria
Exclusion criteria: Failed to complete the screening procedures; Were seropositive for HIV; Tuberculous meningitis; Had risk factors for serious steroid-related adverse events (a history of diabetes or positive urine glucose, a history or clinical finding of hypertension, or a history of peptic ulcer disease or mental illness); Standard doses of antituberculosis drugs could not be used (as in participants with concurrent liver disease); Psychiatric illness; Alcoholism.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Presence of pleural thickening;Death rate;Pulmonary function at completion of treatment;Adverse drug effect; | — |
Countries
China
Contacts
Public ContactShi huanzhong
Outcome results
None listed