catheter related bladder discomfort
Conditions
Interventions
control group:no solifenacin after surgery
test group:given solifenacin after surgery
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Men or women aged 18 to 60 years; 2. Patients undergoing endoscopic surgery for renal or ureteral calculis and received double-J stent and catheter insertion through the urethra intraoperatively; 3. patients who complained of CRBD on the 0 day(baseline); 4. Voluntary participation and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Severe dysfunction of heart,lung,liver and other vital organs; 2. surgical history of lower urinary tract; 3. Medical history of lower urinary tract symptoms; 4. Neurogenic bladder, urethral dysfunction, bladder outflow obstructionmyasthenia gravis, ulcerative colitis, Narrow angle glaucoma and other circumstances that are not suitable for the medicine; 5. use of muscarinic receptor antagonist within the late 30 days; 6. Allergic to any composition of the study drug; 7. Women in pregnancy and lactation; 8. morbid obesity; 9. history of drug abuse; 10. Chronic pain and long-term use of analgesic medicine; 11. Unsuitable patients judged by investigators.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| occurrence of CRBD; | — |
Secondary
| Measure | Time frame |
|---|---|
| occurrence of CRBD after surgery;urgency episodes per 24 hours;quality of life;urge incontinence episodes per 24 hours;The incidence of adverse reaction;mild, moderate, and severe urgency episodes per 24 hours; | — |
Countries
China
Contacts
Public ContactWang Kun Jie
Outcome results
None listed