seasonal allergic rhinitis (Lung and Spleen Qi deficiency type (TCM zheng))
Conditions
Interventions
High dose:High dose of Qidan Bimin Wan
Low dose:Low dose of Qidan Bimin Wan
Sponsors
Orental Hospital, Beijing University of TCM
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. The patient to be confirmed with seasonal allergic rhinitis, the course more than 2 years, onseted in special season, less than two months during each onset and less than one week in this onset; 2. According to the TCM zheng "Lung and Spleen deficiency"; 3. Aged 18 to 60 years; 4. Positive response for skin point puncture test (seasonal allergens) and/or serum special IgE test with positive response; 5. At least two nose main symptoms with moderate and higher grade (higher than 2 scorse); 6. Signed informed consent.
Exclusion criteria
Exclusion criteria: 1. The patient with severe liver and kideny disease or liver and kideny function obviousely abnormal (ALT=2ULN, Cr>ULN); 2. Patient with upper resperitory tract infection, chronic obstructive pulmonary disease, pulmonary fibrosis, asthma (expect mild intermittent asthma (according to the NAEPP guideline); 3. chronic or intermittent use section, oral, intramuscular injection, intravenous injection, and/or super powerful or topical corticosteroids; 4. Use long-term antihistamines; 5. Taking illegal drugs or for certain categories of drug withdrawal time is insufficient: Intranasal or systematically use of corticosteroids less than one month; Intranasal used coloring nucleotide less than two weeks; Intranasal or systematically used of decongestant agent less than 3 days; Intranasal or systematically used antihistamines less than 3 days; Used loratadine less than 10 days; 6. Patient with non allergic rhinitis, sinusitis, nasal polyps, correlation severe nasal septum deviation, eye infections; 7. Patient has diabetes history or fast blood surgar level higher than the higher threshold of normal volue; 8. Patient long term use along with medicines, such as tricyclic antidepressants; 9. Patient with allergy history to test drugs ingredients; 10. Patient attended other clinical study within 3 months before include this trial; 11. Patient with severe mental and neurological diseases; 12. Patient with uncontrolled hypertention; 13. Pregnancy, lactation period woman, or childbearing age woman unable to use effective measures for contraception; 14. Person has illicit drugs history; Or the person who has a history of alcoholism and during the test cannot terminate alcoholics; 15. Any person who to be considered not suite to attending this research.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| All nose symptoms score; | — |
Secondary
| Measure | Time frame |
|---|---|
| All nose symptoms and local physical signs;Eyes along with symptoms scores;Local physical signs (nasal cavity examination) scores;TCM signs scores;Single symptom clearance rate;Quality of life;Remission time of all nose symptom; | — |
Countries
China
Contacts
Public ContactOu Yi
Outcome results
None listed