End stage renal disease
Conditions
Interventions
Low flux hemodialysis:Low flux hemodialysis
High flux hemodialysis:High flux hemodialysis
Hemoperfusion:Hemoperfusion
Sponsors
The People's Liberation Army General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. 18 years and older, male or female; 2 Maintenance hemodialysis over 3 months; 3. Maintenance hemodialysis scheduled 2-3 times a week; 4. Autogenous arteriovenous fistula for vascular access; 5. IPTH> 300pg/ml; 6. ?2-microglobulin> 20mg/L; 7. Signed written informed consent.
Exclusion criteria
Exclusion criteria: 1. Platelet <60*10^9/L; 2. Blood flow <200ml/min; 3. Combined with other clotting disorders, severe bleeding tendency, active bleeding; 4. Hypotension, severe cardiopulmonary dysfunction; 5. Dialyzer or perfusion membrane allergic reactions, contraindications or can not be tolerated; 6. Current or recent (within 30 days) under research of other drugs; 7. Acute infection, serious heart, lung, liver, nervous system disease, acute and critical disease and malignancy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PTH;?2-microglobulin;Leptin;Homocysteine;glycosylation end product; | — |
Countries
China
Contacts
Public ContactXiangmei Chen
Outcome results
None listed