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The effect of Chinese Herbal Medicine (JiaWeiLiuJunZiTang) on Non-motor Symptoms in Idiopathic Parkinson’s Disease (PD): A Randomized Controlled Trial

The effect of Chinese Herbal Medicine (JiaWeiLiuJunZiTang) on Non-motor Symptoms in Idiopathic Parkinson’s Disease (PD): A Randomized Controlled Trial

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-13003085
Enrollment
Unknown
Registered
2013-02-28
Start date
2012-12-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson's disease

Interventions

Treatment:JWLJZT + routine western medications

Sponsors

Food and Health Bureau, Hong Kong S.A.R.
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
40 Years to 79 Years

Inclusion criteria

Inclusion criteria: Patients will be included if they have all the following: a. Meet UKPDBB criteria; b. Age of 18 to 80 years (inclusive); c. Meet the diagnosis of DSQ; d. Stable treatment with levodopa, alone or in combination with other antiparkinsonian drugs over the last 2 months; e. A PD rating of 1.5 to 4 on the Modified Hoehn and Yahr scale; f. Normal liver and renal function in blood test.

Exclusion criteria

Exclusion criteria: Patients will be excluded if they have one or more of the following: a. Atypical or secondary Parkinsonism; b. Use of antidepressants during the preceding month; c. History of psychosis; d. Suicide attempts during the preceding 12 months, or a severe suicidal tendency (score ? 3 on HAM-D item 3, suicide); e. Mini-Mental State Examination (MMSE) < 24; f. Severe diseases (i.e. cancer and acute present asthma); f. Allergy to Chinese herbal medicine; g. Pregnancy or are breast feeding.

Design outcomes

Primary

MeasureTime frame
NMSS;MDS-UPDRS part;

Secondary

MeasureTime frame
PDQ-39;DSQ;MDS-UPDRS part 2-4;SF-36;

Contacts

Public ContactLi Min
bucmpd@hkbu.edu.hk+852 34112919

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026