Ulcer after Endoscopic Submucosal Dissection
Conditions
Interventions
Control:placebo
Sponsors
Chinese PLA General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 70 years old or 18 years old and over; 2. Normal blood coagulation; 3. Meet the ESD indications; 4. Able and willing to provide signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients who have previous hemorrhage of upper digestive tract; 2. Patients who have other serious diseases; 3. Uncontrolled serious diseases of heart, liver, lung, renal and so on; 4. Patients who have used drugs inhibition acid or mucosal protective agents; 5. Patients who have to use other drugs; 6. Patients who had attend other clinical trails; 7. Allergy to pantoprazolelansoprazole or rebamipide; 8. Pregnant or lactating women; 9. Alcoholism or drug addiction patients; 10. Serious complications after ESD, such as bleeding or infection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| healing rate of ulcer;VEGF;EGF;PGE2;COX-2;IL-6, IL-8; | — |
Countries
China
Contacts
Public ContactYang Yunsheng
Outcome results
None listed