postoperative nausea and vomiting
Conditions
Interventions
Acupuncture group:P6 at both sides is punctured perpendicularly 20 mm. Needls are retained for 30 min and stimulated every 10 min to keep the de qi sensation
Sham-acupuncture control group:Sham point at both sides is punctured perpendicularly 5 mm. Needls are retained for 30 min and no stimulation during the duration.
TENS group:P6 acupoint at both sides is stimulated by actived self-adhesive electrodes for 30 min. The stimulation frequency is set on 2-100 hertz and intensity varies until the patients continue to f
Placebo-TENS control group:P6 acupoint at both sides is placed with inactive self-adhesive electrodes for 30 min
Sponsors
Department of integrative medicine, West China hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) scheduled for neurosurgery requiring opening of the cranium and dura; (2) aged between 18 and 70 years old; (3) American Society of Anesthesiologists (ASA) physical status Classification of?or?; (4) undergoing general anesthesia; (5) no history of PONV and motion sickness; (6) no use of antiemetics 24 h before surgery; (7) willing to participate; (8) had no experience with acupuncture therapies; (9) signed an informed consent form.
Exclusion criteria
Exclusion criteria: (1) nausea or vomiting 24 h before surgery; (2) pregnant women or women in lactation; (3) drug or alcohol abusers; (4) received chemotherapy and radiation therapy during the previous 7 days; (5) cardiac pacemaker; (6) in a phase of the menstrual cycle; (7) refused to accept acupuncture and TENS treatment; (8) mental disorder; (9) had a history of epilepsy and now still taking an antiepileptic medicine; (10) unconscious before the surgery; (11) can not normally communicate; (12) undergoing ventricle or brainstem surgery; (13) had a cerebral perfusion pressure (CPP) less than 50 mmHg or greater than 150 mmHg; (14) poorly controlled diabetes mellitus; (15) bleeding disorders; (16) serious systemic disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of PON; | — |
Secondary
| Measure | Time frame |
|---|---|
| Nausea score;Rescue antiemetic dosage; | — |
Countries
China
Contacts
Public ContactNing Li
Outcome results
None listed