Acute and Chronic Knee Joint Synovitis
Conditions
Interventions
Huamoyan Granules:One sachet each time, three times a day, taken with water
Control:Placebo
Sponsors
Shanghai Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Volunteer to join in the experiment and sign the letter of consent; (2) Age between 18 to 70 years, both male and female; (3) Comply with the diagnosis standard of knee joint synovitis; (4) Comply with differentiation standard of dampness-heat blocking collaterals syndrome; (5) Grading medical image of K-L knee-joint is less than or equal to 3 scores; (6) Average scores of knee-joint pain are between 40 and 70 scores; (7) Course of treatment for acute period is less than or equal to 14 days; Course of treatment for chronic period is more than 14 days.
Exclusion criteria
Exclusion criteria: (1) Diagnosed as dampness and rheumatism or deficiency cold of spleen and stomach; (2) Ready to be pregnant, pregnancy or breasting feeding woman; (3) Diabetic patient; (4) Patients with allergic constitution or allergic to ingredients of test drug; (5) Accompanied with knee osteoarthritis without swollen; blood stagnation in kneel; rheumatic arthritis or rheumatoid arthritis; inflectional arthritis; gout arthritis; synovial tuberculosis; synovioma; hemophilic arthritis; bone tumor; Pigmented villonodular synovitis; thyroid hyperfunction; Osteomalacia;multiple myeloma patients; (6) Patients with drug abuse or alcoholism history, psychiatric history, alzheimer; (7) Accompanied with severe primary disease including heart and cerebral disease, liver, kidney and hematopoietic system; (8) ALT, AST, Cr are more than normal value; (9) Patients with critical severe disease, beyond assessment of efficiency and safety of drug. (10) Patients take other drug to treat synovitis within 3 months before the experiment, take cortin within one week before the experiment. Patients take acupuncture, and physical method to treat disease within one week before the experiment. Patients take some medicine which will effect efficiency and safety in long term and accept comprehensive treatment; (11) Join in other clinical experiment within 3 months before this experiment; (12) Other unqualified patients specified by researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Knee joint swelling point; | — |
Countries
China
Contacts
Public ContactJinxue Wang
Outcome results
None listed