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The effect of combined epidural-intravenous propofol anesthesia on cancer cell proliferation and migration in colon cancer patients: in vitro test and mechanism study

The effect of combined epidural-intravenous propofol anesthesia on cancer cell proliferation and migration in colon cancer patients: in vitro test and mechanism study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR-TRC-12004387
Enrollment
Unknown
Registered
2012-04-06
Start date
2012-05-01
Completion date
Unknown
Last updated
2017-04-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colonic cancer

Interventions

T:total intravenous anesthesia
I:inhalation anesthesia
E:combined epidural-intravenous propofol anesthesia

Sponsors

Sir Run Run Shaw Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 75 Years

Inclusion criteria

Inclusion criteria: Patients who was definitely diagnosed as colorectal cancer or colonic cancer, and proposed for a radical surgery, aged 40-65 years, ASA grade I-II.

Exclusion criteria

Exclusion criteria: Patients who have distant metastasis, with known immunologic disease, or have chemotherapy or radiotherapy before operation, have contraindications of epidural anesthesia, allergic to halide; patients whose surgery lasts more than 4 hours, allogeneic transfusion, temperature less than 34 during surgery.

Design outcomes

Primary

MeasureTime frame
NK cell number;th1/th2;—

Countries

China

Contacts

Public ContactZhou Dachun

Sir Run Run Shaw Hospital,College of Medecine, Zhejiang University

zhoudc86@163.com+86 13588708510

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026